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Often when we feel depressed and hopeless, we experience an extreme loneliness. It appears that no one cares about our situation.
However, this is never the case.
Even if we feel abandoned by everyone, God is always there.
Many in the Bible experienced similar feelings, and in their desperation, they cried out to God.
Here is a prayer from the book of Lamentations that expresses those desperate feelings, while placing trust in God's mercy.